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A comparative account of protein-protein interaction resources, feature-validations and application-based categorizations

PIPs - Human Protein-Protein Interaction Prediction

Tool namePIPs - Human Protein-Protein Interaction Prediction
URLhttp://www.compbio.dundee.ac.uk/www-pips
Important featuresA database specific to human PPIs. Predicts interaction based on co-expression, domain/interfaces/sites, co-localization and co-occurrence of PTMs.
CitationsMcDowall MD, Scott MS, Barton GJ. PIPs: human protein-protein interaction prediction database. Nucleic Acids Res. 2009 Jan;37(Database issue):D651-6. Epub 2008 Nov 6. PubMed PMID: 18988626; PubMed Central PMCID: PMC2686497.
Year of publication2008
Rank by usage frequency100
Comments
FunctionPredicted PPIs based on co-expression, Predicted PPIs based on the domain/interfaces/sites, Predicted PPIs based on co-localization, Inferred PPIs (e.g., human PPIs inferred from mouse), Predicted PPIs based on co-occurrence of PTMs, Predict PPI network in a species by using ortholog information, PPIs and their rank based on evidence score, PPIs along with supporting evidences, Similar PPIs among species, PPIs specific to post translation modifications, PPIs for given protein sequence (BLAST search)
Categoryhttp://www.compbio.dundee.ac.uk/www-pips, A database specific to human PPIs. Predicts interaction based on co-expression, domain/interfaces/sites, co-localization and co-occurrence of PTMs., McDowall MD, Scott MS, Barton GJ. PIPs: human protein-protein interaction prediction database. Nucleic Acids Res. 2009 Jan;37(Database issue):D651-6. Epub 2008 Nov 6. PubMed PMID: 18988626; PubMed Central PMCID: PMC2686497., 2008, 100
Online/downloadable
OnlineOnline
Downloadable
Registration required
FreeFree
Paid
Working statusFunctional
FunctionPredicted PPIs based on the protein structure
Category
Tool_frequency

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